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Current Cerebral Embolic Protection Landscape

Keystone Heart TriGUARD Data Review

Jeffrey Moses

Conclusions:

  • Overt and Covert stroke are significant complications of TAVR which may be of greater consequence as we move in to lower risk, younger populations
  • The weight of evidence indicates that CEP reduces these events
  • By covering al 3 cerebral vessels TriGuard cerebral embolic protection may further reduce risk form that seen in SENTINEL
  • TriGuard cerebral protection is safe and does not add procedural risk
  • Phase 2 of REFLECT is underway and hopefully will give us definitive evidence of clinical efficacy
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